Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange | PNAS
Simulating Ras: 30 years of progress - NCI
Small Molecule Binding Sites on the Ras:SOS Complex Can Be Exploited for Inhibition of Ras Activation | Journal of Medicinal Chemistry
A New Dimension to Ras Function: A Novel Role for Nucleotide-Free Ras in Class II Phosphatidylinositol 3-Kinase Beta (PI3KC2β) Regulation | PLOS ONE
The current state of the art and future trends in RAS-targeted cancer therapies | Nature Reviews Clinical Oncology
The complex RAS circle shows the interconnections and feedback of the... | Download Scientific Diagram
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
The Importance of Mg2+‐Free State in Nucleotide Exchange of Oncogenic K‐Ras Mutants - Pálfy - 2022 - Chemistry – A European Journal - Wiley Online Library
Mechanism-Based Redesign of GAP to Activate Oncogenic Ras | Journal of the American Chemical Society
Recirculating Aquaculture Systems UV Disinfection - ULTRAAQUA
Competitive, connective and allosteric Nanobodies that modulate the SOS1•RAS protein-protein interactions and tune the nucleotide exchange rate as a starting point for drug design | bioRxiv
NIH 3D - Ras:SOS:Ras in complex with a small molecule activator
Small Molecule Binding Sites on the Ras:SOS Complex Can Be Exploited for Inhibition of Ras Activation | Journal of Medicinal Chemistry
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
Atorvastatin inhibits insulin synthesis by inhibiting t | Open-i
ZAYED EDUCATIONAL COMPLEX – RAS AL KHAIMAH
Mechanism-Based Redesign of GAP to Activate Oncogenic Ras | Journal of the American Chemical Society
Frontiers | The Multi-Level Mechanism of Action of a Pan-Ras Inhibitor Explains its Antiproliferative Activity on Cetuximab-Resistant Cancer Cells
Binding of active Ras and its mutants to the Ras binding domain of PI-3-kinase: A quantitative approach to KD measurements - ScienceDirect
Competitive, connective and allosteric Nanobodies that modulate the SOS1•RAS protein-protein interactions and tune the nucleotide exchange rate as a starting point for drug design | bioRxiv
New protein complex structure reveals possible ways to target key cancer pathway | Broad Institute
Targeting RAS phosphorylation in cancer therapy: Mechanisms and modulators - ScienceDirect
Mapping the functional versatility and fragility of Ras GTPase signaling circuits through in vitro network reconstitution | eLife
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
Binding of active Ras and its mutants to the Ras binding domain of PI-3-kinase: A quantitative approach to KD measurements - ScienceDirect
Ras Laffan Petrochemical Project | Chevron Phillips Chemical
Targeting RAS phosphorylation in cancer therapy: Mechanisms and modulators - ScienceDirect
Integrated RAS signaling defined by parallel NMR detection of effectors and regulators | Nature Chemical Biology
